There is about 0.3% mesembrine in the leaves and 0.86% in the stems of the plant.Quality kanna can be ID'ed by the smell (similar to the smell of tobacco), the taste will be bitter to very bitter, depending on the part of the plant(aerial parts being more potent).
These compounds interact with receptors in the brain, enhancing the production of dopamine, which is our primary inner pleasure chemical, and prolonging the activity of serotonin, a critically important mood compound.Mesembrine is a major alkaloid present in Sceletium tortuosum. It is also believed to be a PDE4-inhibitor due to a strikingly similar chemical makeup and effects profile in comparison to a chemical named rolipram.Quality Sceletium tortuosum contains about 1-1.5% - 3.0% total alkaloids, weak kanna is .25% or less.although the process seems to involve crushing/cutting then heating (in the hot sun) rather than actual fermentation action by bacteria. It is important to have a good source of quality kanna, there are big differences in the quality of kanna, "wild crafted" is about equal to "swag", green house/professionally tended is much higher quality and is considered "dank".The alkaloids contained in Kanna are psychoactive they include: mesembrine, mesembrenone, mesembrenol and tortuosamine.The net effect of sceletium ingestion is a feeling of tremendous well being, heightened awareness, mental alertness and a keen-mindedness that is quite pronounced.
But there is far more than just a feel good effect and terrific mental stimulation to sceletium.Soon your mind is overcome with startling clarity, a feeling that anything is possible, and a seemingly endless capacity for ideas and mental work.If coffee is a pick-me-up, sceletium is a jet ride to mental brilliance.The San people used to pick the plant, bury it to ferment it, then dry it.Once dried, sceletium was eaten, used as a snuff or even smoked, to produce its potent effects. A good way to describe the effects of sceletium is through a simple metaphor.Poor kanna will not have much taste and will not have the "loud" smell. Dosing regularly, or daily, will help amplify the effects.